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Furthermore, CAF-derived exosomes, which carry acetic acid, lipids, amino acids, or TCA intermediates, are taken up by pancreatic cancer cells via macropinocytosis and are associated with the inhibition of mitochondrial oxidative phosphorylation and increased compensation of glycolysis

Cell proliferation pathways such as PI3K/AKT/mTOR and NF-B can further enhance anti-apoptotic systems, promoting tumor cell resistance to apoptosis

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doi: 10.1016/j.neuroimage.2008.12.072 70 LawlerP

GHK-Cu is shorthand for the glycyl-L-histidyl-L-lysine copper complex , a small peptide made of three amino acids bound to a single copper ion

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