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doi: 10.1161/CIRCGENETICS.113.000321 113 ShenG.LiL.WangQ

About this article Cite this article Wang, T., Wang, C., Liu, T

[PubMed: 21795446] 48

PMID 37192437 d

Advances in formulation science and delivery technology will be critical to the full exploitation of these naturally occurring compounds for therapeutic advantage in periodontal as well as general oral healthcare ( Nanoformulations and drug delivery systems for polyphenol enhancement Even though polyphenols have great potential for treating periodontal disease, their clinical application is greatly restricted due to problems like not dissolving well in water, breaking down easily in the body, being quickly processed, and not being absorbed well (Figures 6, 7)