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Pregnant or breastfeeding women should avoid MOTS-c given the absence of safety data in these populations, as is standard for all investigational peptide therapies

Research Overview# No human data -- All studies described below are preclinical (cell culture or animal models)

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Am J Phys Regul Integr Comp Phys

Gonadal function

The vast majority of studies have been conducted in rodent models, and while these findings carry genuine scientific weight, the translation of animal research to human outcomes is never guaranteed