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After NLRP3 activation, ASC and pro-caspase-1 assemble the NLRP3 inflammasome, which mediates the self-cleavage of pro-caspase-1 and formation of the active caspase-1 p10/p20 tetramer

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[12] Glutamate receptors serve to facilitate the impact of the neurotransmitter glutamate in the central nervous system