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Unlike oral supplements, which must pass through the digestive system, injections deliver these compounds directly into the bloodstream or muscle for superior absorption and faster results

This study was registered on the PROPERO database as #CRD42022360452

While structural differences may exist for larger, higher-acuity hospitals (such as VHA hospitals and academic medical centers) that could make improved Safety of Care performance more difficult to achieve, we note that these hospitals do tend to both have more Safety of Care measures available and larger volumes for the measures they do have, both factors that increase measure reliability and reduce the possibility of score reductions based on chance variation

Free vitamin B12 then combines with intrinsic factor a substance secreted by the stomach cellswhich enables it to be absorbed from the small intestine

Unopened vials can be stored at room temperature for up to 2 years when kept sealed, dry, and protected from light