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Vitamin B6 assists the process of synthesizing compounds into chemical messengers called neurotransmitters

In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12

People Who Have Had Gastric Surgery Gastric bypass surgery (like Roux-en-Y), sleeve gastrectomy, or other bariatric procedures significantly reduce the stomachs ability to produce intrinsic factor a protein required to absorb B12 in the small intestine