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The primary mechanism of action of these drugs in the treatment of vitiligo is calcineurin inhibition, which causes the transcription of several proinflammatory cytokines essential to the pathophysiology of the early immune response to be disrupted and antigen-specific T-cell reactivity to be downregulated 26

They cost $59 for a one-month supply or $55 per month if you subscribe

Srinivas US, Tan BWQ, Vellayappan BA, Jeyasekharan AD

These neuroprotective effects offer promising therapeutic strategies for neurodegenerative diseases, particularly AD (Yang et al., 2023)

It is also known to lighten the skin by decreasing melanin (the pigment responsible for dark skin) production, resulting in a more even skin tone and fewer dark spots

et al., 2010, Ringseis et al., 2018, Steiber et al., 2004)