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Effect of weight loss on upper airway anatomy and the apnea-hypopnea index

On further probing Madsen found that the tumours secreted an abundance of GLP-1, which he published in a paper together with Holst and others in 1995 (Blume, Skouv, Larson)

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Conversely, restoring MC4R expression in the paraventricular nucleus of MC4R-null mice has been demonstrated to increase energy expenditure and reduce body weight, glucose levels, and insulin levels [63]

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