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Test doses should be administered, followed by an hour of observation prior to administering the remainder of the initial therapeutic dose

Adverse Events/Precautions Rare, but devastating long-term adverse effects of LIS including physical disfigurement and the off-label manner of administration have prevented widespread use of medical-grade LIS

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Research Insight The benzyl alcohol contained in bacteriostatic water helps suppress bacterial growth after the vial has been opened, but it does not prevent peptide degradation

Activation of the GH/IGF-1 axis by CJC-1295, a long acting GHRH analog, results in serum protein profile changes in normal adult subjects

Dosing protocols for disc herniations are extrapolated from studies on other tissues and from clinical experience