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10.1038/s41598-018-35890-7 144 ValentiD.de BariL.de RasmoD.SignorileA.Henrion-CaudeA.ContestabileA.et al (2016)

PMID: 29986520 Seiwerth, S., et al

New insights from single-cell and spatial profiling of tumor cells and tumor immune microenvironment

In hypoxic tumor microenvironments, hypoxia inducible factor 1 subunit alpha (HIF1A, also known as HIF1) represses DLAT expression and confers resistance to cuproptosis 176 , supporting the existence of a HIF1A-DLAT-GSH regulatory axis