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Ensemble-based virtual screening led to the discovery of new classes of potent tyrosinase inhibitors

Mitochondrial glutathione is particularly critical for protecting against oxidative damage, as mitochondria lack the enzymes for glutathione synthesis and must import it from the cytosol via specific transport systems

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Hence, there is growing support for the use of compounds that target only peripheral opioid receptors, avoiding the central nervous system, which helps to reduce the risk of common opioid-related side effects

bw, body weight

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