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Using orthotopic murine breast cancer and melanoma that develop spontaneous LN metastases, we also showed that resection of TDLNs did not prevent ICB responses (63), which was attributed to the rerouting of antigen drainage to distant LNs

In SOD1 G93A mice, a ketogenic diet was shown to protect against the loss of motor neurons in the spinal cord and to delay the onset of behavioral symptoms (Zhao et al., 2006)

88 , 89 Zille et al also believe that not only does erastin itself not have toxic effects, but it may prevent toxicity of the tumor to the central nervous system

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Given the absence of etiology for secondary cholangitis such as infection and neoplasia, the histologic findings are suggestive of primary sclerosing cholangitis (PSC)

J Aquat Anim Health 15(3):229238