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doi: 10.1074/jbc.M702824200 164 ParkJ

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These mutations carried out the conversion of a proto-oncogene into a carcinogenic oncogene, which is responsible for different types of cancer (Marnett, 2000)

Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model