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I know this is another area where you have been a leader in the treatment of neurological disorders

My doctor said this was not a systemic reaction just a local reaction

Ryan PM, Stanton C, Caplice NM

Nicotinamide Preservation 5-Amino-1MQ functions as a NAM-site competitive inhibitor, binding at the active site of NNMT and preventing the enzyme from methylating nicotinamide

These data and data from existing patient datasets were analyzed using bioinformatic tools, including exon-intron-split analysis (EISA), FLUFF and clustering analyses