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The identification of alternative targets of HIF hydroxylases is important in order to fully elucidate the pharmacology of hydroxylase inhibitors (PHI)

Together, these peptides address fibrosis, inflammation, and cellular repairkey factors in renal pathology

NAC might actually act as a pro-oxidant and might lower GSH and increase the amount of oxidized GSH

Next, we examined cellular phenotypes when cells were deprived of glutamine under acidosis

In primary rat hippocampal neurons, changes to endogenous APP cleavage and the abundance of CTFs were once again observed upon RABGAP1 KD (Appendix Fig