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Multivariate hypothesis testing was done using permutational analysis of variance (PERMANOVA)

Conversely, having enough glutathione protects the mitochondria so they can use NAD+ more efficiently

doi:10.1023/B:BEBM.0000035138.85857.3a PMID:15452592 Khavinson VKh, Morozov VG

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2 Conclusions Dose-adjusted and low-intensity treatment are two different forms of dose-reduced DOACs with distinct objectives

While using a cohort of male mice at a single age minimizes potential confounding factors such as fluctuations in sex hormone levels, age-related physiological decline, and underlying comorbiditiesthereby enhancing the stability and reproducibility of the preliminary mechanistic resultsthis design significantly limits the external validity and broader applicability of our conclusions