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Antioxidant enzymes such as Superoxide Dismutase (SOD), Catalase (CAT), and Glutathione Peroxidase (GPx) help to block the initiation of reactive species chain reactions and form the first line of antioxidant defence ( is transferred into H 2 O 2 via the addition of an electron in a reaction catalysed by SOD

Accurate evaluation of the regulatory role of oxidative stress on the production of A production is therefore important for establishing an appropriate therapeutic strategy for DS-related neuronal degeneration