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Lifetime carcinogenicity studies with oral aripiprazole have been conducted in ICR mice and in Sprague-Dawley (SD) and F344 rats

However, it is very likely that, since estimated risk is based on tumour incidence at concentrations that induce irritancy in the respiratory tract and no-observed-effect levels for irritancy are well below these concentrations, the true cancer risk is most likely much lower at concentrations generally present in the environment and may, indeed, be zero

Some lab tests of cancer cells have found that ashwagandha might slow down their growth

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PMID: 41978422 Chem Biol Interact Co-exposure to PS-NPs and HFPO-TA potentiates reproductive toxicity via ferroptosis and SLC1A5-Mediated glutamine deprivation in male mice

The stack as a combined formulation has not been studied in randomised controlled trials