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The aim of this study is to leverage data from the Global Burden of Disease 2021 database to conduct an assessment of temporal trends and epidemiological patterns of smoking-attributable neurodegenerative diseases, Alzheimers disease, other dementias, and multiple sclerosis, across global, regional, and national scales, with a particular focus on age- and sex-stratified disparities

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As a result, the aerosol contains significantly lower levels of HPHCs compared to combustible cigarettes and lower levels, on a nicotine normalized basis, relative to other vapor products