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Signaling pathways modulated by glutathione NRF2/KEAP1 antioxidant response: Oxidation or Sglutathionylation of Keap1 cysteines impairs Nrf2 ubiquitination, allowing Nrf2 stabilization, nuclear translocation, and induction of ARE-driven genes, including GCL subunits, the cystine/glutamate antiporter xCT, and GST isoformscreating a feed-forward elevation of GSH synthesis and conjugation capacity

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Trademark Information: Ceramosides is a registered trademark of EPI France and is used under license from Seppic, Inc

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28 (2), e70137

Exploring the mechanisms of action of the antidepressant effect of the ketogenic diet