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Full names of enzymes and substrates can be found in the supplementary material

For the second ligation, the peptides CSP-14, (3.2 mg, 3.8 10 4 mmol) and CSP-1-3 (2.5 mg, 4.2 10 4 mmol) were dissolved in 100 l of 6 M GnHCl, 200 mM Na 2 HPO 4 buffer, pH ~7.2, containing 20 equiv

This induces pyroptosis and releases IL-1 and IL-18, forming a ferroptosis-pyroptosis positive feedback amplification loop

This suggests that polyphenols are prone to degradation in biological systems, potentially reducing their bioavailability and biological efficacy (110112)

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Monovalent cations: Li + , Na + , K + and NH 4 +