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Description

Mammalian GPX1, GPX2, GPX3, and GPX4 are selenoenzymes

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In addition to perturbed C-C stretching modes in the ~ 10001500 cm 1 region, a strong and distinct absorption appears in the ~ 400600 cm 1 range

Emerging single-cell metabolic profiling supports this by showing that CD34 + AML cells, especially the highly leukemogenic CD34 + CD38 low/ fraction, exhibit low ROS levels but possess high antioxidant GSH levels and enhanced mitochondrial potential (MITO) compared to other fractions [121]

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