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Psychiatry 9, 371385

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These substances are often substances produced by the body (metabolites) that cannot be removed properly due to the impaired function of the kidneys

5.4 Polyphenols Mitochondria are the primary site for the creation of free radicals due to the production of adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS), so elevated oxidative stress in individuals with DS primarily affects these organelles

examining the post-mortem tissue from iLBD, PD and control patients found LBP in all samples from the olfactory bulb and the primary olfactory cortex in iLBD and PD cases [212]