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The activation of these molecules then leads to the recruitment of more downstream molecules, the degranulation of mast cells, and the release of cytokines and eicosanoids

For instance, lactate plays a dual role in aerobic metabolism: it serves not only as an important energy substrate but also contributes to antioxidant defense

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Inflammatory molecules, such as cytokines, signal the immune system to respond to injury or infection

Treatment and prophylaxis

SelS and SelP are the two major selenoproteins of the body implicated in antioxidant defence and selenium transport respectively (Lu and Holmgren, 2009)