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Combined with clinical biomarkers and health history, this supports more personalized supplementation decisions

We need to learn how safe it is over a long time and understand the specific biological pathways that are involved

Extending the BSA paradigm, Fu et al

doi: 10.3389/fendo.2025.1587891 Received 05 March 2025 Accepted 24 June 2025 Published 16 July 2025 Volume 16 - 2025 Edited by Lawrence Merle Nelson, Mary Elizabeth Conover Foundation, Inc., United States Reviewed by Roger Smith, The University of Newcastle, Australia Qinqin Gao, First Hospital of Soochow University, China Updates Copyright 2025 Anti, Gheorghe, Deming, Adeoye, Zhang and Mata-Greenwood

3.3 Cytoskeletal damage and axonal degeneration Cytoskeletal damage and axonal degeneration are key pathological aspects of BIPN

The HCNPs nanoparticle self-assembled to co-deliver a neoantigen peptide (Adpgk) and CpG, specifically targeting dendritic cells for activation (Figure 11A)