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Resveratrol, a polyphenolic stilbene, displays concentration-dependent biphasic actions, at low doses it can weakly mimic estrogenic effects via ER activation, whereas at higher pharmacologic concentrations it acts as an ER antagonist, inhibits aromatase transcription, and disrupts co-activator recruitment to the ER complex, thereby exerting anti-proliferative and pro-apoptotic effects in ER-positive breast cancer cells (192)

The honest summary is that long-term human safety data is missing and the angiogenesis mechanism is an unresolved theoretical concern

Unlike fish oil, where omega-3s are bound to triglycerides, krill oil carries its omega-3s on phospholipids molecules that form the outer layer of human cells

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