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10.1016/s0140-6736(77)90612-2 Lancet

Cases were still included if demographic or clinical variables were missing

We therefore propose that acidification of mutant supernatant (via secretion of acids and impaired urease activity) and changes to extracellular antioxidant composition circumvented the oxidation of L-DOPA, thereby preventing its use in melanin formation by gsh2 mutants

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