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Oxidative Med Cell Longev 2015:756294 Vincent A, Brownlee M, Russel J (2002) Oxidative stress and programmed cell death in diabetic neuropathy

In CNS, adenosine modulates neural development, control of immune system and neuron signalling

[2] Histaminergic neurons, neurons that produce histamine, are key modulators of our sleep and wakefulness

Molecules 27 (8), 2446

This may have translational importance, because human diabetic retinopathy has recently become known to include glial and neuro-nal abnormalities

[5] Arginine HCl Injection is contraindicated in individuals with a known hypersensitivity or allergy to arginine or any of the formulations components