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FEBS Lett 472:196202

Subcutaneous fat is the soft, pinchable layer just under the skin

Many patients report feeling less fatigued, sleeping better, and feeling more rested after starting treatment

Stamler SJ, Jaraki O, Osborne J, Simon DI, Keaney J, et al

Colorimetric analysis revealed a 1.8% increase in L* value (skin lightness) and an 8.7% increase in individual typology angle (ITA) compared with placebo