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These results suggest that HMOX2 localizes to both the ER and MERCs, where it interacts with MITOL

Model substrate 1-chloro-2,4-dinitrobenzene binds with different safeners such as benoxacor, fenclorim and flurazole to enhance GST activity by 3 to 5 folds [68]

Additionally, the authors acknowledge the general positive bias of the published results, the lack of replicative validation studies, and the resulting risk of overestimating treatment efficacy in preclinical models that would provide confidence for the current findings and improve translational significance

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International Journal of Pharmaceutical & Biological Archive

Bioavailability refers to how much of a substance actually enters your bloodstream and becomes available for your body to use