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The ratio between these forms of glutathione is crucially important and is a strong indication of health

The significance of reactive oxygen species and antioxidant defense system in plants: A concise overview

There is evidence that the full inhibition of Complex I that prevents increased ROS generation impairs hypoxic adaptation in tumor cells by rewiring mitochondrial metabolism, and the antitumorigenic effect of ROS signaling is lost [39]

However, the mechanism of iron death involves a variety of factors, including antioxidant system factors, such as GSH and GPX4, which are important mechanisms of iron death [86, 87]

University of Minnesota, 2011

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