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As mentioned previously, the widespread and prolonged use of histamine H 2 -receptor blockers and proton pump inhibitors for ulcer disease also may cause impaired breakdown of vitamin B 12 from food, causing malabsorption and eventual depletion of B 12 stores

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Routine follow-up care during treatment with blood tests and physical exam also helps to ensure safety

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Increased permeability of the gut barrier leads to extensive translocation of microbes into the lamina propria, which is associated with higher circulating levels of LPS (141)

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Oral B12 supplements rely on a complex absorption pathway in the gut involving a protein called intrinsic factor

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Vitamin B12 Dietary Sources Naturally occurring vitamin B12 is usually found in animal products

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Animal products contain vitamin B12 because the animals are given this vitamin in their feed too

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