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Recently, non-covalent inhibitors of SmTGR, presenting antischistosomal efficacy in an animal model of infection, were developed targeting the doorstop pocket (here site S3), which further validates this pocket as a druggable site 96

Such models are useful in studying metabolic and developmental consequences of thyroid hormone deficiencies, giving insight into how thyroid hormone insufficiency impacts growth and neurological function

Hallbergs laser scanning microscopy observations showed significant changes in LipidTOX stained LD distribution during the cleavage of experimentally treated bovine oocytes [34]

doi: 10.1111/jphp.12334

Its deficiency has been linked to impaired social behavior and heightened anxiety-like symptoms in children with ASD (Pivina et al., 2019)

Barnham KJ, Masters CL, Bush AI