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The FDA then evaluates these to ensure the safety and welfare of human subjects

What to monitor Visible changes: Skin texture and tone Fine line depth Hair density and quality Wound healing speed Subjective factors: Energy levels Sleep quality General sense of wellbeing Side effects: Injection site reactions Skin flushing Fatigue (especially early in use) Photograph yourself in consistent lighting at baseline and every 4 weeks

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Though K i values at 5-HT 1A R did not significantly correlate with the ED 50 values for lower-lip retraction or antinociception, the correlation approached significance ( P = 0.0508, Figure 9)