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(3) removal of single nucleotide polymorphisms if they showed a threshold allele frequency 0.01 in either the gnomAD 46 ( or the Japanese Multi Omics Reference Panel (jMorp, 20210907) 47 ( and (iv) registration of mutations as pathogenic/likely pathogenic variants in ClinVar

*Correspondence: Haidong Wang, [email protected]

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The timing can vary, but many find administering in the morning or before exercise convenient

10.1016/j.jhazmat.2014.07.048 37 KrugerN

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