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Propensity score matching was applied to emulate the randomization between GLP-1a and oGLD users while Cox regression models were used to estimate hazard ratio (HR) and 95% confidence interval (CI)

All data were tested for normality (ShapiroWilk test) and homogeneity of variance (Levene test)

Moreover, the p62-kelch-like ECH-associated protein 1 (Keap1)-Nrf2 pathway is associated with ferroptosis

The role of zinc in immune function

Thus, our data reveal the extensive regenerative capacity of the tissue even under genotoxic shock and suggest that targeting of SOX2 + cells might be a therapeutic approach to regenerate tissue damaged by radiation therapy