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The aims of the present study are (i) to characterize the mechanisms and cellular pathways of toxicity induced by reactive QIs of AQ

Impact of Folate Deficiency on the Methionine Cycle A deficiency in folate disrupts this cycle, leading to metabolic imbalances, impaired methylation reactions, and downstream cellular dysfunctions

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Schwaitzberg SD, Roberts K, Romanelli JR, Desilets DJ, Earle D, Horgan S,

A Randomized, Placebo-Controlled Phase III Extension Trial of the Long-Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus