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IGF-1 LR3 plays an important role in cell proliferation, cell-to-cell communication and cell division.IGF-1 LR3 is a derivative of IGF-1

Ghigo E, Arvat E, Muccioli G, Camanni F

But the science gets complicated quickly

Contraindications and Clinical Cautions While generally safe, growth hormone optimization peptides are contraindicated in patients with active malignancies, as IGF-1 can promote the proliferation of existing cancer cells

It binds to growthhormone secretagogue receptors (GHSR) in the hypothalamus and pituitary, reduces the inhibitory signal from somatostatin, and triggers a rapid GH pulse

This prevents condensation from introducing moisture