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For example, it has been shown to: Decrease levels of DNA damage when administered to senescence-accelerated mice [15]

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Moreover, the MSSM levels of WT(pXMJ19-His 6 - mtr ) cells were lower than those of WT(pXMJ19) cells under H 2 O 2 , ciprofloxacin, CdCl 2 and CDNB stresses

Other relevant examples, such as SG1 and HMRef-gal, have been reported to detect -gal expressing cells in vivo, although not limited to cellular senescence 69,72

Phase II Clinical Trial of Off-the-Shelf NK Cells with Allogeneic Stem Cell Transplantation in Patients with High-Risk Myeloid Malignancies | Blood | American Society of Hematology

This heterogeneity has profound implications for therapy, as targeting glycolysis alone will not effectively treat OXPHOS-dependent tumors, and vice versa