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Neuroprotective effects of licorice extracts in tibial and sural transection induced neuropathic pain in rats

The core mechanism consists of an inflammatory cascade: the exposure to LPS initiates the release of pro-inflammatory cytokines, including TNF- and IL-1, as well as the production of ROS, which results in a depletion of GSH

In cells, glutathione is maintained in the reduced form by the enzyme glutathione reductase and in turn reduces other metabolites and enzyme systems, such as ascorbate in the glutathione-ascorbate cycle, glutathione peroxidases and glutaredoxins, as well as reacting directly with oxidants

TREATMENT: Apply the Glutathione on the area to be treated with gentle circular movement

Specialized antigen-presenting cells, such as macrophages and dendritic cells, process, present, and release cytokines to T cells (172)

These findings underscore the indispensable role of the association between TMED10s C-terminal domain (TMED10-CT) and E-SARS2 in the regulation of E-SARS2-mediated UcPS