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Its a small-molecule research compound investigated in studies involving Nicotinamide N-Methyltransferase (NNMT)

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Safety and Research Limitations Importantly, No adequate clinical evidence defines safe human exposure, maximum tolerated dose, reproductive toxicity, carcinogenicity, genotoxicity, cardiovascular risk, liver safety, kidney safety, endocrine effects, or drug interactions

In an experimental model, transgenic mice expressing a kinase-deficient IGF-1R -subunit (thus displaying reduced signal transduction in both IGF-1R and hybrid receptors) developed diabetes early on life [162, 236]

The study showed no changes in physical exams, lab results, glucose levels, glucose tolerance, insulin sensitivity, IGF-1 levels, or adverse event rates

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