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Finally, pharmacological research is needed to ensure that drugs are delivered to the necessary organs, such as the inflammatory joints of RA, with optimum safety and efficiency in a wide range of autoimmune diseases

50,51 This energy deficiency triggers the collapse of the mitochondrial membrane potential ( m ) and the release of proapoptotic factors, which activate the caspase cascade and induce apoptosis or senescence

Altered endothelium-dependent responses in lambs with pulmonary hypertension and increased pulmonary blood flow

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Several molecules, such as monocyte chemoattractant protein-1 (CCL2) and macrophage inflammatory protein-1 (CCL7), can initiate macrophage recruitment and chemotaxis to increase the magnitude of immune responses

These sequences were used as queries to carry out BLASTP 51 analysis to identify the homologues present in Protozoa