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Imdelltras label contains a boxed warning for serious or life-threatening cytokine release syndrome and neurologic toxicity, including immune effector cell-associated neurotoxicity syndrome, according to the FDAs press release

Btker HE, Hausenloy D, Andreadou I, Antonucci S, Boengler K, Davidson SM, Deshwal S, Devaux Y, Di Lisa F, Di Sante M, Efentakis P, Femmin S, Garca-Dorado D, Giricz Z, Ibanez B, Iliodromitis E, Kaludercic N, Kleinbongard P, Neuhuser M, Ovize M, Pagliaro P, Rahbek-Schmidt M, Ruiz-Meana M, Schlter K-D, Schulz R, Skyschally A, Wilder C, Yellon DM, Ferdinandy P, Heusch G (2018) Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

Castenholz RW, Wilmotte A, Herdman M, Rippka R, Waterbury JB, Iteman I, Hoffmann L (2001) Phylum BX

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Precision therapy for ulcerative colitis: insights from mitochondrial dysfunction interacting with the immune microenvironment

So, we have expectation, anxiety, how well we've slept, where we are in the so-called 24-hour circadian time, and our genes