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The absence of TMA in the urine of germ-free mice without microbiota, 66 the suppression of TMAO production from dietary choline 22 and carnitine 19 in mice treated with broad-spectrum antibiotics, and the re-increase in plasma TMAO levels after antibiotic withdrawal clearly indicate the role of gut microbiota in TMA and TMAO production

Wang, "Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact", PLOS ONE 10 (e0136574): 1-16 (2015)

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