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Besides, as was discussed for ACE inhibitors, an analogous additive effect of Cd on ion channeltargeting pesticides can be hypothesised [118]

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PEG-induced osmotic stress caused significant changes in metabolite profiles of both genotypes, with key stress-related compounds including flavonoids, phenolic acids, alkaloids, nucleotides, peptides, lipids, fatty acids and amines accumulating to a greater extent in LY46 than in HGN

Table 1 A model of diverse roles of plant GSTs in four different interaction types between plant hosts and pathogenic microbes

Such studies move closer to the goal of precision therapy for asthma by targeting intracellular nodes, such as ERK1/2, rather than broad anti-inflammatory agents, and hold promise for improved management of severe and therapy-resistant forms of this prevalent and debilitating disease