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However, glutathione redox potential ( E GSH ) of Col-0 became less negative after 24 h of 100 M SA treatment (by 13 mV [ 292.44 mV] in PM and 8 mV [ 303.41 mV] in EZ), in comparison to 10 M of SA treatment, which caused 11 mV ( 294.10 mV) and 6 mV ( 304.81 mV) shifts in the PM and EZ, respectively

S1G), findings further supported by elevated serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) (Fig

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However, whether peripheral mechanisms, together with or independent of other central pathways, also participate in morphine-induced colonic hypomotility requires further investigation in future studies