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Beyond its energy role, NAD+ is the essential substrate of sirtuins (SIRT1-SIRT7), deacetylases that regulate mitochondrial biogenesis, DNA repair, and resistance to cellular stress (Imai & Guarente, Trends Cell Biol 2014)

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In our opinion, most families try CAM because they hear about it in the media, perceive it as natural, and are eager to leave no stones unturned in their efforts to manage autism symptoms