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Under physiological conditions, LCACs have the capacity to regulate the current amplitude and kinetics of hERG channels in the heart, which have important effects on arrhythmia [121]

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Martinotti, G., Andreoli, S., Reina, D., Di, Nicola M., Ortolani, I., Tedeschi, D., Fanella, F., Pozzi, G., Iannoni, E., D'Iddio, S., and Prof, L

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Nitric oxide is the endothelial factor responsible for relaxation of smooth musculature surrounding the arterials and the pre-capillary sphincters thereby producing vasodilation and increased blood flow into the capillary bed of the exercising muscle tissue

org/10.3390/jpm12071053 Pennisi, M., Lanza, G., Cantone, M., D'Amico, E., Fisicaro, F., Puglisi, V., Vinciguerra, L., Bella, R., Vicari, E., & Malaguarnera, G