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A primate-specific functional GTTT-repeat in the core promoter of CYTH4 is linked to bipolar disorder in human

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Results Ozz and Alix localize to mitochondria, and their individual loss disrupts mitochondrial morphology Given that Alix is a substrate of CRL5 Ozz we aimed to determine whether the loss of Alix in skeletal muscle would lead to myofiber defects similar to those observed in the skeletal muscle of the original Ozz / mouse line 31

Initially, injections are given daily or every other day for a week, then weekly for 12 months, followed by monthly maintenance

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