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Imidazole looks just like the side chain of histidine residues, so excess concentrations of imidazole, usually 250 to 500 mM imidazole, are used to elute his-tagged proteins from the nickel agarose beads (Figure 3)

Wang B, Han J, Elisseeff JH, Demaria M

This KDTA 11 also largely survived treatment with an excess of the common disulfide cleavage reagent TCEP (tris-(2-carboxyethyl)phosphine)

Increased IL-1 levels elevate iron regulatory protein 1 and TFR1 in oligodendrocytes, while reduced iron transporter protein 1 expression leads to intracellular iron accumulation, contributing to neurodegenerative diseases (Yang J

Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression

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